Responding to Antimicrobial Resistance with Novel Therapeutics
نویسندگان
چکیده
منابع مشابه
Novel Strategies to Combat Antimicrobial Resistance
Infectious diseases form the major health-care burden for the developing world and antimicrobials prove to be the magical drugs to combat this. The discovery of antimicrobial agents was boon for the global health-care system and the wonderful cure by antimicrobials shifted the disease trends from infectious to life-style diseases in the developed world. Sudden appearance of the antimicrobial re...
متن کاملNovel Methods to Address Antimicrobial Resistance
Whilst many governments are placing restrictions on antibiotic use [4], this is too little, too late. The current situation has made the quest for new antibiotics and antibiotic alternatives a matter of great importance. Given the development costs, the complexity in finding new drug targets, and the timescales involved, the prospect of antibiotic alternatives remains low; therefore, greater pr...
متن کاملIncreasing antimicrobial resistance and narrowing therapeutics in typhoidal salmonellae.
Multidrug-resistant typhoid fever (MDRTF) is a major public health problem in developing countries and is an emerging problem in the developed world. Because of the difficulties in preventing typhoid by public health measures or immunization in developing countries, great reliance is placed on antimicrobial chemotherapy. The treatment should commence as soon as the clinical diagnosis is made ra...
متن کاملResistance to Antimicrobial Agents
The main reason for the current unsatisfactory situation is that, worldwide, there is no effective regulation of the use of antibiotics. In many nations drugs are freely available "over the counterî and even in countries where most drugs are only available on prescription there may be little control. The practice in some societies of doctors prescribing the most potent drug available just in ca...
متن کاملAntimicrobial Therapeutics in Critical Care
The purpose of this manuscript is to summarise current issues in antimicrobial therapeutics, specifically relating to antibacterial drugs, in the critical care setting. Antimicrobial taxonomy, mode of action, pharmacokinetics and pharmacodynamics are important considerations in choosing the most appropriate agent for treatment of infections. Adverse effects of antibiotics can range from mild ga...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Microbiology
سال: 2019
ISSN: 0966-842X
DOI: 10.1016/j.tim.2019.01.007